Review



oir rats  (STATA Corporation)


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    Structured Review

    STATA Corporation oir rats
    Intraperitoneal genipin inhibits retinal UCP2, increases retinal Glut1, and <t>reduces</t> <t>AVA</t> of <t>OIR</t> pups. Western blots of (A, B) UCP2 and (C, D) Glut1 in retinas, and (E, F) AVA of p14 OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A, C) Representative gel images. (B, D) Quantification of densitometry. (E) Representative flat mount images. (F) quantification of AVA; *P < 0.05, **P < 0.01 versus. Control; n = 5–6 for Western blots and n = 14–16 for AVA.
    Oir Rats, supplied by STATA Corporation, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/oir rats/product/STATA Corporation
    Average 99 stars, based on 1 article reviews
    oir rats - by Bioz Stars, 2026-04
    99/100 stars

    Images

    1) Product Images from "Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity"

    Article Title: Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity

    Journal: Investigative Ophthalmology & Visual Science

    doi: 10.1167/iovs.19-26553

    Intraperitoneal genipin inhibits retinal UCP2, increases retinal Glut1, and reduces AVA of OIR pups. Western blots of (A, B) UCP2 and (C, D) Glut1 in retinas, and (E, F) AVA of p14 OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A, C) Representative gel images. (B, D) Quantification of densitometry. (E) Representative flat mount images. (F) quantification of AVA; *P < 0.05, **P < 0.01 versus. Control; n = 5–6 for Western blots and n = 14–16 for AVA.
    Figure Legend Snippet: Intraperitoneal genipin inhibits retinal UCP2, increases retinal Glut1, and reduces AVA of OIR pups. Western blots of (A, B) UCP2 and (C, D) Glut1 in retinas, and (E, F) AVA of p14 OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A, C) Representative gel images. (B, D) Quantification of densitometry. (E) Representative flat mount images. (F) quantification of AVA; *P < 0.05, **P < 0.01 versus. Control; n = 5–6 for Western blots and n = 14–16 for AVA.

    Techniques Used: Western Blot

    Intraperitoneal genipin to reduce AVA reduces intravitreal neovascularization. (A) and (B) IVNV at p18 of OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A) Representative flat mount images and (B) quantification of IVNV; *P < 0.05 versus Control. Scale bar: 990 μm. (C, D) IVNV at p18 of OIR pups treated with control or genipin from p14 to p18. (C) Representative flat mount images and (D) quantification of IVNV. Scale bar: 990 μm, n = 3–16.
    Figure Legend Snippet: Intraperitoneal genipin to reduce AVA reduces intravitreal neovascularization. (A) and (B) IVNV at p18 of OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A) Representative flat mount images and (B) quantification of IVNV; *P < 0.05 versus Control. Scale bar: 990 μm. (C, D) IVNV at p18 of OIR pups treated with control or genipin from p14 to p18. (C) Representative flat mount images and (D) quantification of IVNV. Scale bar: 990 μm, n = 3–16.

    Techniques Used:

    Intraperitoneal genipin increases retinal function. Ganzfeld ERG of (A) a-wave amplitude and (B) b-wave amplitudes in p26 RA and OIR pups after overnight dark adaptation and treatment with control or genipin from p3 to p13 (*P < 0.05, ***P < 0.001 versus RA/Control; †† P < 0.01, ††† P < 0.001 versus OIR/Control; n = 4–6 for ERG and n = 11 for AVA and IVNV); and quantification of (C) AVA and (D) IVNV of OIR pups at p26 treated with control or genipin from p3 to p13.
    Figure Legend Snippet: Intraperitoneal genipin increases retinal function. Ganzfeld ERG of (A) a-wave amplitude and (B) b-wave amplitudes in p26 RA and OIR pups after overnight dark adaptation and treatment with control or genipin from p3 to p13 (*P < 0.05, ***P < 0.001 versus RA/Control; †† P < 0.01, ††† P < 0.001 versus OIR/Control; n = 4–6 for ERG and n = 11 for AVA and IVNV); and quantification of (C) AVA and (D) IVNV of OIR pups at p26 treated with control or genipin from p3 to p13.

    Techniques Used:



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    Image Search Results


    Intraperitoneal genipin inhibits retinal UCP2, increases retinal Glut1, and reduces AVA of OIR pups. Western blots of (A, B) UCP2 and (C, D) Glut1 in retinas, and (E, F) AVA of p14 OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A, C) Representative gel images. (B, D) Quantification of densitometry. (E) Representative flat mount images. (F) quantification of AVA; *P < 0.05, **P < 0.01 versus. Control; n = 5–6 for Western blots and n = 14–16 for AVA.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity

    doi: 10.1167/iovs.19-26553

    Figure Lengend Snippet: Intraperitoneal genipin inhibits retinal UCP2, increases retinal Glut1, and reduces AVA of OIR pups. Western blots of (A, B) UCP2 and (C, D) Glut1 in retinas, and (E, F) AVA of p14 OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A, C) Representative gel images. (B, D) Quantification of densitometry. (E) Representative flat mount images. (F) quantification of AVA; *P < 0.05, **P < 0.01 versus. Control; n = 5–6 for Western blots and n = 14–16 for AVA.

    Article Snippet: A mixed effects linear regression model was used to statistically analyze data collected from OIR rats for AVA and IVNV using STATA-14 software (StataCorp LLC, College Station, TX, USA).

    Techniques: Western Blot

    Intraperitoneal genipin to reduce AVA reduces intravitreal neovascularization. (A) and (B) IVNV at p18 of OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A) Representative flat mount images and (B) quantification of IVNV; *P < 0.05 versus Control. Scale bar: 990 μm. (C, D) IVNV at p18 of OIR pups treated with control or genipin from p14 to p18. (C) Representative flat mount images and (D) quantification of IVNV. Scale bar: 990 μm, n = 3–16.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity

    doi: 10.1167/iovs.19-26553

    Figure Lengend Snippet: Intraperitoneal genipin to reduce AVA reduces intravitreal neovascularization. (A) and (B) IVNV at p18 of OIR pups received intraperitoneal injections of genipin or control from p3 to p14. (A) Representative flat mount images and (B) quantification of IVNV; *P < 0.05 versus Control. Scale bar: 990 μm. (C, D) IVNV at p18 of OIR pups treated with control or genipin from p14 to p18. (C) Representative flat mount images and (D) quantification of IVNV. Scale bar: 990 μm, n = 3–16.

    Article Snippet: A mixed effects linear regression model was used to statistically analyze data collected from OIR rats for AVA and IVNV using STATA-14 software (StataCorp LLC, College Station, TX, USA).

    Techniques:

    Intraperitoneal genipin increases retinal function. Ganzfeld ERG of (A) a-wave amplitude and (B) b-wave amplitudes in p26 RA and OIR pups after overnight dark adaptation and treatment with control or genipin from p3 to p13 (*P < 0.05, ***P < 0.001 versus RA/Control; †† P < 0.01, ††† P < 0.001 versus OIR/Control; n = 4–6 for ERG and n = 11 for AVA and IVNV); and quantification of (C) AVA and (D) IVNV of OIR pups at p26 treated with control or genipin from p3 to p13.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity

    doi: 10.1167/iovs.19-26553

    Figure Lengend Snippet: Intraperitoneal genipin increases retinal function. Ganzfeld ERG of (A) a-wave amplitude and (B) b-wave amplitudes in p26 RA and OIR pups after overnight dark adaptation and treatment with control or genipin from p3 to p13 (*P < 0.05, ***P < 0.001 versus RA/Control; †† P < 0.01, ††† P < 0.001 versus OIR/Control; n = 4–6 for ERG and n = 11 for AVA and IVNV); and quantification of (C) AVA and (D) IVNV of OIR pups at p26 treated with control or genipin from p3 to p13.

    Article Snippet: A mixed effects linear regression model was used to statistically analyze data collected from OIR rats for AVA and IVNV using STATA-14 software (StataCorp LLC, College Station, TX, USA).

    Techniques: